Overview
CJC-1295 with DAC (Drug Affinity Complex) is a modified GHRH analogue in which a maleimidoproprionic acid (MPA) linker covalently binds the peptide to circulating serum albumin. This albumin-binding technology dramatically extends the half-life from ~30 minutes (CJC-1295 No DAC) to approximately 6–8 days, enabling sustained GH release between administrations in animal models. It is a critical research tool for studying long-duration GHRH receptor stimulation and comparing pulsatile vs. sustained GH release patterns.
| Modification | MPA Drug Affinity Complex (DAC) — albumin binding linker |
| Molecular Weight | ~3647.29 g/mol |
| CAS Number | 863288-34-0 (base peptide) |
| Purity | ≥99% (HPLC verified) |
| Format | Lyophilized powder |
| Quantity | 2mg per vial |
| Storage | -20°C, protect from light |
Key Research Applications
- Long-duration GHRH receptor stimulation studies
- Sustained vs. pulsatile GH release comparative research
- Albumin-binding pharmacokinetic modeling
- Somatotroph axis and IGF-1 production studies
- Once-weekly administration protocol research
- Growth hormone deficiency animal models
Reconstitution: Add 1 mL of sterile bacteriostatic water. Gently swirl — do not shake. Store reconstituted peptide at 4°C and use within 14 days.
Research Use Only. This product is intended strictly for in vitro laboratory research. Not for human or veterinary use. Not evaluated by the FDA.
Researcher Resources
- cjc 1295 research overview — Mechanism & Published Research
- How to Reconstitute Peptides — Step-by-Step Researcher Guide
- Science & Quality — HPLC ≥99% Purity Standards
For laboratory research purposes only. Not for human consumption. These statements have not been evaluated by the U.S. Food and Drug Administration.
COA Available on Request
Lot-Specific Testing
Endocrinology Research Unit –
CJC-1295 with DAC shows good sustained release profile in our assays. Purity verified at 99.1% by our in-house HPLC.