Overview
GHK-Cu (Glycyl-L-histidyl-L-lysine : Copper) is a naturally occurring copper-binding tripeptide first isolated from human plasma. It coordinates a single Cu²⁺ ion and has demonstrated a remarkably broad range of biological activities in preclinical research, including promotion of collagen and glycosaminoglycan synthesis, angiogenesis stimulation, anti-inflammatory activity, and regulation of gene expression across hundreds of genes. GHK-Cu declines with age in human plasma, making it a central subject in skin biology, wound healing, and geroscience research.
| Sequence | H-Gly-His-Lys-OH · Cu²⁺ |
| Molecular Formula | C₁₄H₂₃CuN₆O₄⁺ |
| Molecular Weight | 403.92 g/mol |
| CAS Number | 49557-75-7 |
| Purity | ≥99% (HPLC verified) |
| Format | Lyophilized powder |
| Quantity | 50mg per vial |
| Storage | -20°C, protect from light and moisture |
Key Research Applications
- Collagen and glycosaminoglycan synthesis studies
- Skin fibroblast activation and wound healing research
- Angiogenesis and vascularization models
- Anti-inflammatory gene expression studies
- Antioxidant superoxide dismutase pathway research
- Nervous system protection and nerve regeneration models
Reconstitution: Add 2 mL of sterile water for research preparations. Gently swirl — do not shake. Store reconstituted solution at 4°C and use within 14 days. Avoid repeated freeze-thaw cycles.
Research Use Only. This product is intended strictly for in vitro laboratory research. Not for human or veterinary use. Not evaluated by the FDA.
Researcher Resources
- ghk cu research overview — Mechanism & Published Research
- How to Reconstitute Peptides — Step-by-Step Researcher Guide
- Science & Quality — HPLC ≥99% Purity Standards
For laboratory research purposes only. Not for human consumption. These statements have not been evaluated by the U.S. Food and Drug Administration.
COA Available on Request
Lot-Specific Testing
Skin Biology Lab –
GHK-Cu for collagen synthesis assays — works exactly as published literature suggests. Bastion’s vial is clean, the certificate matches, and shipping was professional.