Overview
DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide first isolated from rabbit cerebral blood in 1977 during EEG studies of delta-wave sleep. This nine amino acid peptide is found throughout the CNS, hypothalamus, and peripheral tissues, and has been studied for its roles in sleep regulation, hypothalamic-pituitary axis modulation, and stress response attenuation. DSIP exhibits complex neuroendocrine activity and remains an active subject of research in sleep science, nociception, and peptidergic signaling.
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| Molecular Formula | C₃₅H₄₈N₈O₁₅ |
| Molecular Weight | 848.82 g/mol |
| CAS Number | 62568-57-4 |
| Purity | ≥99% (HPLC verified) |
| Format | Lyophilized powder |
| Quantity | 5mg per vial |
| Storage | -20°C, protect from light |
Key Research Applications
- Sleep architecture and delta-wave EEG studies
- Hypothalamic-pituitary axis neuroendocrine research
- Stress response and cortisol attenuation models
- GH and LH release modulation studies
- Nociception and pain signal pathway investigation
- Opioid system interaction research
Reconstitution: Add 1 mL of sterile bacteriostatic water. Gently swirl — do not shake. Store reconstituted peptide at 4°C and use within 14 days.
Research Use Only. This product is intended strictly for in vitro laboratory research. Not for human or veterinary use. Not evaluated by the FDA.
Researcher Resources
- dsip research overview — Mechanism & Published Research
- How to Reconstitute Peptides — Step-by-Step Researcher Guide
- Science & Quality — HPLC ≥99% Purity Standards
For laboratory research purposes only. Not for human consumption. These statements have not been evaluated by the U.S. Food and Drug Administration.







Sleep Research Lab –
DSIP compound was analytically pure. Used in delta wave induction experiments. Packaging and cold chain maintained throughout transit.